منابع مشابه
Iron-overload myopathy.
A 66-year-old male patient presented with a 4-month history of progressive muscle weakness. Twelve years prior to presentation he was evaluated for fatigue, weight loss, new-onset diabetes and elevated liver enzymes and was diagnosed with hereditary hemochromatosis, homozygous for the C282Y mutation in the HFE gene. His total iron at diagnosis was 137 mcg/dL; iron binding capacity, 149 mcg/dL; ...
متن کاملIron overload.
Dietary copper in the U.S. often is lower than that proved insufficient for men and women under controlled conditions. Iron overload can have adverse effects on copper nutriture and can produce cardiac disease in people. The hypothesis that iron can interfere with copper utilization to produce adverse effects related to cardiovascular function was tested. Rats were fed a diet high in iron and m...
متن کاملIron Deficiency and Iron Overload.
Iron is essential to most, if not all, living organisms, and the higher animals and man have employed it for many purposes essential to life. The readiness with which iron undergoes oxidation and reduction is utilized in many of the enzymes of electron transport, and in a number of other enzymes whose function is not understood. Furthermore, the combination of iron with porphyrin and protein le...
متن کاملHydrophilic Phytochelators in Iron Overload Condition
Background: Iron overload can cause many complications and damage many organs as well as physiologic functions. Consumption of phetochemicals and flavonoids with iron chelating ability, instead of synthetic iron chelators, can be less harmful and more effective. The aim of this review is to investigate hydrophilic phytochelators in iron overload condition. Methods: In this review, the possible ...
متن کاملDiagnosing myocardial iron overload.
Cardiac failure or arrhythmia are the dominant causes of death in patients with thalassaemia major and other transfusion-dependent refractory anaemias. Each unit of blood contains 200–250 mg of iron and body iron stores are normally only 0·5–1·5 g. Since the body has no physiological mechanism for excreting iron, repeated blood transfusions result in iron accumulation in the reticuloendothelial...
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ژورنال
عنوان ژورنال: International Journal of Hematology
سال: 2011
ISSN: 0925-5710,1865-3774
DOI: 10.1007/s12185-011-0961-1